黄荷凤，中国科学院院士，英国皇家妇产科学院荣誉院士，发展中国家科学院院士，中国医学科学院学部委员。 复旦大学、浙江大学和上海交通大学讲席和特聘教授，博士生导师，主任医师，澳大利亚Adelaide大学和香港大学客座教授。973首席科学家，十二五国家科技支撑计划牵头人，863项目负责人，国家自然科学基金基础科学中心共同PI、重大国际合作项目负责人，国家重点研发计划重点专项负责人。教育部“生殖遗传”重点实验室主任，上海市胚胎源性疾病重点实验室主任。中国妇幼保健协会副会长，国际生殖遗传学会（ISRG）创会理事。在Nature 、Nature Medicine和PNAS等SCI杂志发表论文300余篇，以第一完成人完成国家科技进步奖两项。
主要科研项目 Medical Research Council项目，OPTIMISE: Optimal preconception nutrition to offset inflammation and non-communicable disease risk in pregnant women and their children，2020.5.1-2025.4.30，1879830.81英镑，参与； 国家自然科学基金（基础科学中心项目），82088102，能量代谢与健康，2021.01-2025.12，6000万，在研，共同PI； 国家重点研发计划，2017YFC1001303，“生殖健康及重大出生缺陷防控研究”重点专项：人类胚胎发育中的细胞编程与配子/胚胎源性疾病的发生机制，2017.07-2020.12，1482万，已结题，主持； 国家自然科学基金（中加合作），81661128010，中加合作健康生命轨迹计划：预防儿童肥胖的社区-家庭-母婴综合干预队列研究，2017.01-2021.12，1500万，已结题，项目负责人； 国家自然科学基金（面上项目），31471405，雄激素对TET介导的卵母细胞去甲基化影响及传代效应机制研究，2015.01-2018.12，80万，已结题，项目负责人； 国家自然科学基金（应急管理项目），81450038，AR基因pre-mRNA剪接变体导致排卵障碍转录调控机制研究，2015.01-2015.12，40万，已结题，项目负责人； 国家自然科学基金（重大项目），81490742，胚胎着床过程中母-胎互作关键调控通路的生理和病理作用机制，2015.01-2019.12，317万，已结题，项目负责人； 国家重点基础研究发展规划（973 计划)，2013CB967404，性分化异常疾病与生殖干细胞转换相关性和机制研究，2013.01-2017.12，已结题，参加人员； 国家重点基础研究发展计划（973计划），2012CB944900，辅助生殖诱发胚胎源性疾病的风险评估和机制研究，2012.01-2016.12，2598万，已结题，首席科学家； "十二五“国家科技支撑计划，2012BA132B00，生殖建康状况评估及关键技术研究，2012.01-2016.12，4400万，已结题，主持； 国家自然科学基金（面上项目），31171444，高糖对人胚胎干细胞向胰岛细胞分化过程中Igf1/H19差异甲基化区的调控及效应机制研究，2012.01-2015.12，60万，已结题，项目负责人； 国家自然科学基金（面上项目），30973209，妊娠期宫内高糖环境对子代亲源性基因印记的影响及其遗传效应机制的研究，2010.01-2012.12，30万，已结题，项目负责人； 国家自然科学基金（中加健康研究合作），30711120577，卵细胞源性生长因子对人类卵泡发育调节机制的研究，2008.01-2010.12，45万，已结题，项目负责人； 国家高技术研究发展计划（863计划），2007AA02Z456，积极性优生途径——植入前胚胎基因诊断技术的临床应用和推广，2007.06-2010.11，550万，已结题，项目负责人； 国家自然科学基金（面上项目），30670789，Ca2+激活K2+通道在人子宫内膜细胞的表达，功能及其在胚胎着床中的作用，2007.01-2009.12，28万，已结题，项目负责人。
代表性论文（#第一作者，*通讯作者） Bin Chen#, Ya-Rui Du#, Hong Zhu#, Mei-Ling Sun#, Chao Wang#, Yi Cheng, Haiyan Pang, Guolian Ding, Juan Gao, Yajing Tan, Xiaomei Tong, Pingping Lv, Feng Zhou, Qitao Zhan, Zhi-Mei Xu, Li Wang, Donghao Luo, Yinghui Ye, Li Jin, Songying Zhang, Yimin Zhu, Xiaona Lin, Yanting Wu, Luyang Jin, Yin Zhou, Caochong Yan, Jianzhong Sheng, Peter R. Flatt, Guo-Liang Xu *& Hefeng Huang*. Maternalinheritance of glucose intolerance via oocyte TET3 insufficiency. Nature. 2022May;605(7911):761-766. Chenming Xu#, Jianli Li#, Songchang Chen#, Xiaoqiang Cai#, Ruilin Jing, Xiaomei Qin, Dong Pan, Xin Zhao, Dongyang Ma, Xiufeng Xu, Xiaojun Liu, Can Wang, Bingxin Yang, Lanlan Zhang, Shuyuan Li, Yiyao Chen, Nina Pan, Ping Tang, Jieping Song, Nian Liu, Chen Zhang, Zhiwei Zhang, Xiang Qiu, Weiliang Lu, Chunmei Ying, Xiaotian Li, Congjian Xu, Yanlin Wang, Yanting Wu*, He-Feng Huang*, Jinglan Zhang*. (2022). Genetic deconvolution of fetal and maternal cell-free DNA in maternal plasma enables next-generation non-invasive prenatal screening. Cell discovery, 8(1), 109. Yanting Wu#, Chen Zhang, Han Liu, Chenchi Duan, Cheng Li, Jianxia Fan, Hong Li, Lei Chen, Hualin Xu, Xiangjuan Li, Yi Guo, Yeping Wang, Xiufeng Li, Jing Li, Ting Zhang, Yiping You, Hongmei Li, Shuangqi Yang, Xiaoling Tao, Yajuan Xu, Haihong Lao, Ming Wen, Yan Zhou, Junying Wang, Yuhua Chen, Diyun Meng, Jingli Zhai, Youchun Ye, Qinwen Zhong, Xiuping Yang, Dan Zhang, Jing Zhang, Xifeng Wu, Wei Chen, Cindy-Lee Dennis, He-Feng Huang*. Perinatal depressive and anxiety symptoms of pregnant women during the coronavirus disease 2019 outbreak in China. American Journal of Obstetrics and Gynecology. 2020;223(2). PMID: 32437665. Yanting Wu#, Chenjie Zhang, Hefeng Huang*. Authors' reply re: Coronavirus disease 2019 among pregnant Chinese women: case series data on the safety of vaginal birth and breastfeeding.BJOG: an international journal of obstetrics and gynaecology, 128(10), 1711–1712. PMID: 34114326. Yu Zhang#, Chao Zhang#, Jing Shu, Jing Guo, Hsun-Ming Chang, Peter C K Leung*, Jian-Zhong Sheng, Hefeng Huang*. Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis. Human Reproduction Update. 2020;26(2):247-63. PMID: 32045470. Huan Zhao#, Yan Li, Lingjuan He, Wenjuan Pu, Wei Yu, Yi Li, Yan-Ting Wu, Chenming Xu, Yuda Wei, Qiurong Ding, Bao-Liang Song, Hefeng Huang*, Bin Zhou*.In Vivo AAV-CRISPR/Cas9-Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia. Circulation. 2020;141(1):67-79. PMID: 31779484. Xi Chen#, Hui Lin#, Daping Yang, Wei Xu, Guangwei Liu, Xinmei Liu*, Jianzhong Sheng*, Hefeng Huang*. Early-life undernutrition reprograms CD4(+) T-cell glycolysis and epigenetics to facilitate asthma. Journal of Allergy and Clinical Immunology. 2019;143(6):2038. PMID: 30654047. Hong Zhu#, Bin Chen#, Yi Cheng, Yin Zhou, Yi-Shang Yan, Qiong Luo, Ying Jiang, Jian-Zhong Sheng, Guo-Lian Ding*, He-Feng Huang*. Insulin Therapy for Gestational Diabetes Mellitus Does Not Fully Protect Offspring From Diet-Induced Metabolic Disorders. Diabetes. 2019;68(4):696-708. PMID: 30696708. Dan-dan Wu#, Ling Gao#, Ou Huang#, Kamran Ullah, Meng-xi Guo, Ye Liu, Jian Zhang, Lei Chen, Jian-xia Fan, Jian-zhong Sheng, Xian-hua Lin, He-feng Huang*. Increased Adverse Pregnancy Outcomes Associated With Stage 1 Hypertension in a Low-Risk Cohort Evidence From 47 874 Cases. Hypertension. 2020;75(3):772-80. PMID: 32008433. Yan-Ting Wu#, Jun Liu#, Jing-Jing Xu#, Yan-Fen Chen#, Wen Yang, Yang Chen, Cheng Li, Yu Wang, Han Liu, Chen Zhang, Ling Jiang, Zhao-Xia Qian, Andrew Kawai, Ben Willem Mol, Cindy-Lee Dennis, Guo-Ping Xiong*, Bi-Heng Cheng*, Jing Yang*, He-Feng Huang*. Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China. Plos Medicine. 2020;17(7).PMID: 32722722. Yan-Ting Wu#, Chen-Jie Zhang#, Ben Willem Mol, Andrew Kawai, Cheng Li, Lei Chen, Yu Wang, Jian-Zhong Sheng, Jian-Xia Fan, Yi Shi*, He-Feng Huang*. Early Prediction of Gestational Diabetes Mellitus in the Chinese Population via Advanced Machine Learning. Journal of Clinical Endocrinology & Metabolism. 2021;106(3):E1191-E205. PMID: 33351102. Xian-hua Lin#, Dan-dan Wu#, Cheng Li, Yi-jing Xu, Ling Gao, Geffen Lass, Jian Zhang, Shen Tian, Deyana Ivanova, Lin Tang, Lei Chen, Rong Ding, Xi-mei Liu, Mi Han, Jian-xia Fan, Xiao-feng Li, Jian-zhong Sheng, Kevin T. O’Byrne, and He-feng Huang*. Maternal High Triglyceride Levels During Early Pregnancy and Risk of Preterm Delivery: A Retrospective Cohort Study. Journal of Clinical Endocrinology & Metabolism. 2019;104(4):1249-58. PMID: 30321365. Danni Zheng#, Lin Zeng#, Rui Yang#, Ying Lian, Yi-Min Zhu, Xiaoyan Liang, Li Tang, Huichun Wang, Yunxia Cao, Guimin Hao, Jianqiao Liu, Junli Zhao, Rui Wang, Ben Willem Mol, Rong Li, He-Feng Huang*, Jie Qiao*. Intracytoplasmic sperm injection (ICSI) versus conventional in vitro fertilisation (IVF) in couples with non-severe male infertility (NSMI-ICSI): protocol for a multicentre randomised controlled trial. Bmj Open. 2019;9(9). PMID: 31575574. Xue-Ying Zhang#, Yi-Meng Xiong#, Ya-Jing Tan, Li Wang, Rong Li, Yong Zhang, Xin-Mei Liu, Xian-Hua Lin, Li Jin, Yu-Ting Hu, Zhen-Hua Tang, Zheng-Mu Wu, Feng-Hua Yin, Zheng-Quan Wang, Ye Xiao, Jian-Zhong Sheng, He-Feng Huang*. Melatonin rescues impaired penetration ability of human spermatozoa induced by mitochondrial dysfunction. Reproduction. 2019;158(5):465-75. PMID: 31505459. Chen Zhang#,Xi Yang,Yong Zhang,Fei Guo, Shuai Yang,Robin P. Peeters, Tim I. M. Korevaar,Jianxia Fan* and He-Feng Huang*. Association Between Maternal Thyroid Hormones and Birth Weight at Early and Late Pregnancy. Journal of Clinical Endocrinology & Metabolism. 2019;104(12):5853-63. PMID: 31216012. Dan-Qing Yu#,Ping-Ping Lv,Yi-Shang Yan, Guan-Xin Xu,Annapurna Sadhukhan, Shan Dong, Yan Shen, Jun Ren, Xue-Ying Zhang, Chun Feng, Yi-Ting Huang, Shen Tian, Yin Zhou,Yi-Ting Cai, Zhen-Hua Ming, Guo-Lian Ding, Hong Zhu, Jian-Zhong Sheng, Min Jin*, and He-Feng Huang*. Intrauterine exposure to hyperglycemia retards the development of brown adipose tissue. Faseb Journal. 2019;33(4):5425-39. PMID: 30759346. Yin-Yu Wang#, Ye Liu, Cheng Li, Jing Lin, Xin-Mei Liu, Jian-Zhong Sheng & He-Feng Huang*. Frequency and risk factors for recurrent gestational diabetes mellitus in primiparous women: a case control study. Bmc Endocrine Disorders. 2019;19. PMID: 30767767. Ye Liu#, Yinyu Wang#, Fangfang Wang, Jiexue Pan, Jingjing Xu, Jingyi Li, Chengliang Zhou, Guolian Ding, Yanting Wu, Xinmei Liu, Jianzhong Sheng & Hefeng Huang*. Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants. Science China-Life Sciences. 2019;62(2):257-67. PMID: 30767767. Xiang-Juan Li#, Hai-Tao Pan#, Juan-Juan Chen, Yi-Bin Fu, Min Fang, Guo-Hua He, Tao Zhang, Hai-Gang Ding, Bin Yu, Yi Cheng, Ya-Jing Tan, Fa-Lin Zhao, Abraham N. Morse, and He-Feng Huang*. Proteomics of Uterosacral Ligament Connective Tissue from Women with and without Pelvic Organ Prolapse. Proteomics Clinical Applications. 2019;13(4). PMID: 30516354. Ziru Jiang#, Li Jin#, Weihui Shi, Ji Xi, Yulian Hu, Xinmei Liu, Jianzhong Sheng, Guolian Ding* & Hefeng Huang*. A combination of follicle stimulating hormone, estradiol and age is associated with the pregnancy outcome for women undergoing assisted reproduction: a retrospective cohort analysis. Science China-Life Sciences. 2019;62(1):112-8. PMID: 29980904. Min Hou#, Hang-Chao Gu#, Hui-Hui Wang, Xin-Mei Liu, Cheng-Liang Zhou, Qian Yang, Zi-Ru Jiang, Jing Lin, Yi-Mei Wu, Yan-Ting Wu, Jian-Zhong Sheng, He-Feng Huang*. Prenatal exposure to testosterone induces cardiac hypertrophy in adult female rats through enhanced Pkc delta expression in cardiac myocytes. Journal of Molecular and Cellular Cardiology. 2019;128:1-10. PMID: 30641088. X-Y Guo#, J Shu, X-H Fu, X-P Chen, L Zhang, M-X Ji, X-M Liu, T-T Yu, J-Z Sheng, H-F Huang*. Improving the effectiveness of lifestyle interventions for gestational diabetes prevention: a meta-analysis and meta-regression. Bjog-an International Journal of Obstetrics and Gynaecology. 2019;126(3):311-20. PMID: 30216635. Cheng-Liang Zhou#, Gu-Feng Xu, Qian Yang, Hui-Hui Wang, Meng-Xi Guo, Yi-Meng Xiong, Xiao-Yan Guo, Min Hou, Lu-Yang Jin, Jian-Zhong Sheng, Lin He, Li Jin*, He-Feng Huang*. Diminished verbal ability among children conceived through ART with exposure to high serum estradiol in utero. Journal of Assisted Reproduction and Genetics. 2020;37(8):1931-8.PMID: 32519010. Chuan-Jin Yu#, Xia Liu#, Zhi-Yang Zhou, Xiao-Jun Chen, Yi-Cong Meng, Hang-Chao Gu, Jing-Jing Xu, Guo-Lian Ding, Xin-Mei Liu*, Jian-Zhong Sheng*, He-Feng Huang*. The casein kinase 2 alpha promotes the occurrence polycystic ovary syndrome. Biochemical and Biophysical Research Communications. 2020;525(1):121-8.PMID: 32081430. Caochong Yan#, Yunxiang Zhou#*, Qiang Chen, Yi Luo, John H Zhang*, Hefeng Huang*, Anwen Shao*. Dysfunction of the neurovascular unit in diabetes-related neurodegeneration. Biomedicine & Pharmacotherapy. 2020;131.PMID: 32841897. Rui-Hong Xue#, Xian-Hua Lin, Dan-Dan Wu, He-Feng Huang*. Monitoring maternal triglyceride concentrations during pregnancy could be useful in reducing perinatal mortality. Acta Obstetricia Et Gynecologica Scandinavica. 2020;99(9):1262. PMID: 32232828. Rui-Hong Xue#, Juan Li#, Zhen Huang, Zheng-Zheng Li, Lei Chen, Qin Lin, He-Feng Huang*. Is tubal endometriosis an asymmetric disease? A 17-year retrospective study. Archives of Gynecology and Obstetrics. 2020;301(3):721-7. PMID: 32114673. Yan-Ting Wu#, Cheng Li, Chen-Jie Zhang, He-Feng Huang*, FRCOG. Is termination of early pregnancy indicated in women with COVID-19? European Journal of Obstetrics & Gynecology and Reproductive Biology. 2020;251:271-2. PMID: 32456886. Yan-Ting Wu#, Ze-Han Dong#, Cheng Li#, Dai-Zhan Zhou, Jun-Yu Zhang, Yan Wu, Jing-Jing Xu, Yu Wang, Xiao-Qun Ye, Jian-Zhong Sheng , Li Wang, He-Feng Huang*. The effect of blastomere loss during frozen embryo transfer on the transcriptome of offspring's umbilical cord blood. Molecular Biology Reports. 2020;47(11):8407-17. PMID: 33068229. Yaoyao Tu#, Guangyong Zheng#, Guolian Ding, Yanting Wu, Ji Xi, Yingzhou Ge, Hangchao Gu, Yingyu Wang, Jianzhong Sheng, Xinmei Liu*, Li Jin* and Hefeng Huang*. Comparative Analysis of Lower Genital Tract Microbiome Between PCOS and Healthy Women. Frontiers in Physiology. 2020;11. PMID: 33013474. Xia Liu#, Changfa Sun#, Kexin Zou, Cheng Li, Xiaojun Chen, Hangchao Gu, Zhiyang Zhou, Zuwei Yang, Yaoyao Tu, Ningxin Qin, Yiran Zhao, Yimei Wu, Yicong Meng, Guolian Ding, Xinmei Liu*, Jianzhong Sheng, Chuanjin Yu*, Hefeng Huang*. Novel PGK1 determines SKP2-dependent AR stability and reprograms granular cell glucose metabolism facilitating ovulation dysfunction. Ebiomedicine. 2020;61. PMID: 33096483. Jing Lin#, Han Liu#, Dan-Dan Wu, Hong-Tao Hu, Hui-Hui Wang, Cheng-Liang Zhou, Xin-Mei Liu, Xiao-Jun Chen, Jian-Zhong Sheng & He-Feng Huang*. Long interpregnancy interval and adverse perinatal outcomes: A retrospective cohort study. Science China-Life Sciences. 2020;63(6):898-904. PMID: 31701403. Jing-Yi Li#, Yi-Feng Liu#, Hai-Yan Xu, Jun-Yu Zhang, Ping-Ping Lv, Miao-E Liu, Yan-Yun Ying, Ye-Qing Qian, Kun Li, Cheng Li, Yun Huang, Gu-Feng Xu, Guo-Lian Ding, Yu-Chan Mao, Chen-Ming Xu, Xin-Mei Liu, Jian-Zhong Sheng, Dan Zhang*, and He-Feng Huang*. Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. Journal of Molecular Cell Biology. 2020;12(1):71-83. PMID: 31065688. Mengxi Guo#, Chengliang Zhou, Gufeng Xu, Lin Tang, Yechun Ruan, Ying Yu, Xianhua Lin, Dandan Wu, Hao Chen, Priscilla Yu, Luyang Jin, Yinyu Wang, Yimei Wu, Kamran Ullah, Tanzil Ur Rahman, Xinmei Liu, Jianzhong Sheng, Hsiao-Chang Chan*, Hefeng Huang*. An alternative splicing variant of mineralocorticoid receptor discovered in preeclampsia tissues and its effect on endothelial dysfunction. Science China-Life Sciences. 2020;63(3):388-400. PMID: 31197761. WeiGu#,JingLin, Yan-YanHou, NanLin, Meng-FanSong, Wei-JianZeng, JingShang, He-FengHuang*. Effects of low-dose aspirin on the prevention of preeclampsia and pregnancy outcomes: A randomized controlled trial from Shanghai, China. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2020;248:156-63. PMID: 32217429. Ling Gao#, Dandan Wu#, Yanting Wu, Zuwei Yang, Jianzhong Sheng, Xianhua Lin*, Hefeng Huang*. MiR-3940-5p promotes granulosa cell proliferation through targeting KCNA5 in polycystic ovarian syndrome. Biochemical and Biophysical Research Communications. 2020;524(4):791-7. PMID: 32019676. Chen-Chi Duan#, Cheng Li#, Yi-Chen He, Jing-Jing Xu, Chao-Yi Shi, Hong-Tao Hu, Yun-Fei Su, Lei Chen, Ya-Jing Tan, Zhi-Wei Liu, Jian-Zhong Sheng, William D. Fraser, Yan-Ting Wu* and He-Feng Huang*. Oocyte exposure to supraphysiological estradiol during ovarian stimulation increased the risk of adverse perinatal outcomes after frozen-thawed embryo transfer: a retrospective cohort study. Journal of Developmental Origins of Health and Disease. 2020;11(4):392-402. PMID: 31679538. Luting Chen#, Huixi Chen, Xinmei Liu, Jingyi Li, Qian Gao, Shuai Shi, Tingting Wang, Xiaoqun Ye，Yongchao Lu, Dan Zhang, Jianzhong Sheng, Li Jin*, Hefeng Huang*. AQP7 mediates post-menopausal lipogenesis in adipocytes through FSH-induced transcriptional crosstalk with AP-1 sites. Reproductive Biomedicine Online. 2020;41(6):1122-32. PMID: 33132060. Chen-Chi Duan#, Cheng Li#, Yi-Chen He, Jing-Jing Xu, Chao-Yi Shi, Hong-Tao Hu, Yun-Fei Su, Lei Chen, Ya-Jing Tan, Zhi-Wei Liu, Jian-Zhong Sheng, William D. Fraser, Yan-Ting Wu*, and He-Feng Huang*. Oocyte exposure to supraphysiological oestradiol during ovarian stimulation increased the risk of adverse perinatal outcomes after frozen-thawed embryo transfer: a retrospective cohort study. Journal of developmental origins of health and disease. 2020 Aug;11(4):392-402. PMID: 31679538. Zuwei Yang#, Wenzhong Zhou#, Chengliang Zhou#, Yuzhong Zhou, Xinmei Liu, Guolian Ding, Yulian Hu, Jiexue Pan, Jianzhong Sheng, Li Jin*, Hefeng Huang*. Steroid metabolome profiling of follicular fluid in normo- and hyperandrogenic women with polycystic ovary syndrome. Journal of Steroid Biochemistry and Molecular Biology. 2021;206. PMID: 33340681. Yi-Shang Yan#, Zihao Qu#, Dan-Qing Yu, Wei Wang, Shigui Yan*, He-Feng Huang*. Sex Steroids and Osteoarthritis: A Mendelian Randomization Study. Frontiers in Endocrinology. 2021;12. PMID: 34248845. Rui-Hong Xue#, Dan-Dan Wu#, Cheng-Liang Zhou, Lei Chen, Juan Li, Zheng-Zheng Li, Jian-Xia Fan, Xin-Mei Liu, Xian-Hua Lin*, He-Feng Huang, FRCOG*. Association of high maternal triglyceride levels early and late in pregnancy with adverse outcomes: A retrospective cohort study. Journal of Clinical Lipidology. 2021;15(1):162-72. PMID: 33144084. Yanting Wu#, Isabelle Marc#, Luigi Bouchard, Fengxiu Ouyang, Zhong-Cheng Luo, Jianxia Fan, Lise Dubois, Benoît Mâsse, Jun Zhang, Peter C K Leung, Xiang Peng Liao, C M Herba, Linda Booij, Jian Shen, Antoine Lewin, Hong Jiang, Liping Wang, Jian Xu, Weibin Wu, Wenguang Sun, Jiahao Wu, Hong Li, Chen Lei, Anita Kozyrskyj, Sonia Semenic, N Chaillet, Isabel Fortier, Louise Masse, Janelle Zhan, Catherine Allard, Bartha Knoppers, Ma'n Zawati, Jean-Patrice Baillargeon, Maria P Velez, Hanqiu Zhang, Yamei Yu, Wen Yu, Yan Ding, Caroline Vaillancourt, Han Liu, Amelie Tetu, Wenli Fang, Rong Zhang, Xinzhi Zhao, Yan Jin, Xin-Mei Liu, Huijuan Zhang, Zhirou Chen, Xi Yang, Yan-Hui Hao, Nadia Abdelouahab, William Fraser*, He-Feng Huang*. Study protocol for the Sino-Canadian Healthy Life Trajectories Initiative (SCHeLTI): a multicentre, cluster-randomised, parallel-group, superiority trial of a multifaceted community-family-mother-child intervention to prevent childhood overweight and obesity. BMJ Open. 2021;11(4). PMID: 33795307. Hai-Yan Wu#, Yi Cheng, Lu-Yang Jin, Yin Zhou, Hai-Yan Pang, Hong Zhu, Cao-Chong Yan, Yi-Shang Yan, Jia-En Yu, Jian-Zhong Sheng, He-Feng Huang*. Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation. Molecular and Cellular Endocrinology. 2021;529. PMID: 33811969. Yinyu Wang#, Yiting Mao#, Yiran Zhao, Xianfu Yi, Guolian Ding, Chuanjin Yu, Jianzhong Sheng, Xinmei Liu, Yicong Meng* and Hefeng Huang*. Early-life undernutrition induces enhancer RNA remodeling in mice liver. Epigenetics & Chromatin. 2021;14(1). PMID: 33789751. Yaoyao Tu#, Guangyong Zheng#, Guolian Ding, Yanting Wu, Ji Xi, Yingzhou Ge , Hangchao Gu, Yingyu Wang, Jianzhong Sheng, Xinmei Liu*, Li Jin* and Hefeng Huang*. Comparative Analysis of Lower Genital Tract Microbiome Between PCOS and Healthy Women (vol 11, 1108, 2020). Frontiers in Physiology. 2021;11. PMID: 33013474. Chang-Fa Sun#, Han Liu, Yan-Hui Hao, Hong-Tao Hu, Zhi-Yang Zhou, Ke-Xin Zou, Xin-Mei Liu, Jian-Zhong Sheng, Guo-Lian Ding, He-Feng Huang*. Association between gestational anemia in different trimesters and neonatal outcomes: a retrospective longitudinal cohort study. World Journal of Pediatrics. 2021;17(2):197-204. PMID: 33625695. Ningxin Qin#, Zhiyang Zhou#, Wenlong Zhao#, Kexin Zou, Weihui Shi, Chuanjin Yu, Xia Liu, Zehan Dong, Yiting Mao, Xinmei Liu, Jianzhong Sheng, Guolian Ding, Yanting Wu* and Hefeng Huang*. Abnormal Glucose Metabolism in Male Mice Offspring Conceived by in vitro Fertilization and Frozen-Thawed Embryo Transfer. Frontiers in Cell and Developmental Biology. 2021;9. PMID: 33634140. Yiting Mao#, Chen Zhang#, Yinyu Wang, Yicong Meng, Lei Chen, Cindy-Lee Dennis, Jianzhong Sheng, Yanting Wu* and Hefeng Huang*. Association Between Paternal Age and Birth Weight in Preterm and Full-Term Birth: A Retrospective Study. Frontiers in Endocrinology. 2021;12. PMID: 34367073. Ye Liu#, Xinzhu Li#, Songchang Chen, Li Wang, Yajing Tan, Xiaocui Li, Lin Tang, Junyu Zhang, Dandan Wu, Yanting Wu, Xinmei Liu, Yimin Zhu, Jianzhong Sheng, Jiexue Pan*, Li Jin* and Hefeng Huang*. Comparison of Genome-Wide DNA Methylation Profiles of Human Fetal Tissues Conceived by in vitro Fertilization and Natural Conception. Frontiers in Cell and Developmental Biology. 2021;9. PMID: 34336842. Han Liu#, Hong Li, Cheng Li, Lei Chen, Chenjie Zhang, Zhiwei Liu, Yanting Wu*, Hefeng Huang*. Associations between Maternal Sleep Quality Throughout Pregnancy and Newborn Birth Weight. Behavioral Sleep Medicine. 2021;19(1):57-69. PMID: 31830816. Xian-Hua Lin#, Ling Gao, Shen Tian, Christian Klausen, Meng-Xi Guo, Qian Gao, Miao-E Liu, Hui Wang, Dan-Dan Wu, Cheng-Liang Zhou, Jing Yang, Ye Meng, Ye Liu, Gu-Feng Xu, Ya-Jing Tan, Kamran Ullah, Yi-Min Zhu, William D Fraser, Jian-Zhong Sheng, Peter C K Leung, Louis J Muglia, Yan-Ting Wu*, He-Feng Huang*. Maternal high-fat-diet exposure is associated with elevated blood pressure and sustained increased leptin levels through epigenetic memory in offspring. Scientific Reports. 2021;11(1). PMID: 33431976. Yinlam Li#, Li Zhang#, Xiaoguo Zheng, Jianing Qian, Yanquan Li, Chong Xie, Xuelian Zhang*, Yuchuan Zhou*, Hefeng Huang*. Dietary restriction and/or exercise training impairs spermatogenesis in normal rats. Applied Physiology Nutrition and Metabolism. 2021;46(3):229-37. PMID: 32905708. Cheng Li#, Jing-Jing Xu#, Hong-Tao Hu, Chao-Yi Shi, Chuan-Jin Yu, Jian-Zhong Sheng, Yan-Ting Wu*, He-Feng Huang*. Amylin receptor insensitivity impairs hypothalamic POMC neuron differentiation in the male offspring of maternal high-fat diet-fed mice. Molecular Metabolism. 2021;44. PMID: 33279727. Luyang Jin#, Jia’en Yu#, Yuxiao Chen, Haiyan Pang, Jianzhong Sheng* and Hefeng Huang*. Polycystic Ovary Syndrome and Risk of Five Common Psychiatric Disorders Among European Women: A Two-Sample Mendelian Randomization Study. Frontiers in Genetics. 2021;12. PMID: 34211505. Yingzhou Ge#, Chen Zhang, Yanqing Cai*, Hefeng Huang*. Adverse Maternal and Neonatal Outcomes in Women With Elevated Intrapartum Temperature Complicated by Histological Chorioamnionitis at Term: A Propensity-Score Matched Study. Frontiers in Pediatrics. 2021;9. PMID: 34368025. Ying-Zhou Ge#, Chen Zhang, Yan-Qing Cai*, He-Feng Huang*. Application of the RCOG Risk Assessment Model for Evaluating Postpartum Venous Thromboembolism in Chinese Women: A Case-Control Study. Medical Science Monitor. 2021;27. PMID: 34230447. Yiting Mao, Yiran Zhao, Sisi Luo, Huixi Chen, Xia Liu, Ting Wu, Guolian Ding, Xinmei Liu, Jianzhong Sheng, Yicong Meng, Hefeng Huang*. Advanced paternal age increased metabolic risks in mice offspring. Biochim Biophys Acta Mol Basis Dis. 2022 Feb 4;1868(5):166355. PMID: 35131436. Si-Si Luo, Ke-Xin Zou, Hong Zhu, Yi Cheng, Yi-Shang Yan, Jian-Zhong Sheng, He-Feng Huang*, Guo-Lian Ding*. Integrated Multi-Omics Analysis Reveals the Effect of Maternal Gestational Diabetes on Fetal Mouse Hippocampi. Frontiers in cell and developmental biology.2022;10:748862. Chen-Chi Duan, Cheng Li, Jing-Jing Xu, Yi-Chen He, Hua-Lin Xu, Dan Zhang, Jia-Qi Yang, Jia-Le Yu, Wan-Ting Zeng, Ying Wang, Lei Chen, Cindy-Lee Dennis, Yan-Ting Wu, He-Feng Huang*. Association between prenatal exposure to ambient air pollutants and postpartum depressive symptoms: A multi-city cohort study [published online ahead of print, 2022 Jan 22]. Environ Res. 2022;209:112786. Xiaoyue Cheng, Xinhua Ji, Dongjian Yang, Chen Zhang, Lei Chen, Cong Liu, Xia Meng, Weidong Wang, Huichu Li, Haidong Kan, Hefeng Huang*. Associations of PM2.5 exposure with blood glucose impairment in early pregnancy and gestational diabetes mellitus. Ecotoxicology and environmental safety[J]. 2022,232, 113278. Haiyan Xu, Jingyi Li, Luyang Jin, Dan Zhang, Bin Chen, Xinmei Liu, Xianhua Lin, Yiting Huang, Zhanghong Ke, Juan Liu, Lin Gao, Jianzhong Sheng, Hefeng Huang*. Intrauterine hyperglycemia impairs endometrial receptivity via up-regulating SGK1 in diabetes. Science China, Life sciences[J], 10.1007/s11427-021-2035-2. Advance online publication.
代表性著作 Huang H F, Sheng J Z. Gamete and Embryo-fetal Origins of Adult Diseases [M].. Springer Netherlands, 2013. ISBN 978-94-007-7772-9. 主编； 乔杰, 黄荷凤. 妇产科学（第2版）（英文改编版）[M]. 科学出版社, 2020. ISBN 978-7-03-066940-7. 786千字. 改编； 黄荷凤. 实用人类辅助生殖技术[M]. 人民卫生出版社, 2018. ISBN 978-7-117-27228-5. 1271千字. 主编； 黄荷凤. 植入前遗传学诊断临床实践[M]. 上海交通大学出版社, 2018. ISBN 978-7-313-19681-1/R. 221千字. 主编； 黄荷凤. 宝贝快来·27位权威专家解析不孕不育[M]. 浙江科学技术出版社, 2016. ISBN 978-7-5341-6981-6. 主编； 乔杰. 生殖医学临床诊疗常规[M]. 人民军医出版社, 2013. 副主编； 徐键. 妇产科常见疾病诊治指南（上篇）[M]. 浙江大学出版社, 2010. 名誉主编； 中华医学会. 临床诊疗指南:辅助生殖技术与精子库分册[M]. 人民卫生出版社, 2009. ISBN 978-7-117-11984-9/R. 263千字. 主编； 中华医学会. 临床技术操作规范:辅助生殖技术与精子库分册[M]. 人民军医出版社, 2010. ISBN 978-7-5091-3519-8. 105千字. 副主编； 黄荷凤, 张治芬, 张松英. 辅助生育技术怀孕指南[M]. 人民军医出版社, 2004. ISBN 9787801578662. 主编； 黄荷凤. 现代辅助生育技术[M]. 人民军医出版社, 2003. ISBN 7-80157-809-0. 655千字. 主编； 黄荷凤. 高危妊娠[M]. 人民军医出版社, 2003. ISBN 7-80157-724-8. 主编； 黄荷凤, 韩秀君. 流产[M]. 农村读物出版社, 2000. ISBN 7-5048-3216-2, 9787504832160. 主编； 黄荷凤, 陈丹青. 月经不调[M]. 农村读物出版社, 2000. ISBN 7-5048-3199-9. 主编； 黄荷凤.《生殖医学》，人民出版社，2021年，ISBN 978-7-117-31354-4,主编
获奖 2020年，发育源性疾病和遗传性出生缺陷的机制研究及临床精准防控，中华人民共和国国务院，国家科学技术进步奖二等奖，第一完成人（1/10）； 2011年，不孕症病因及治疗方法的研究与临床应用，中华人民共和国国务院，国家科学技术进步奖二等奖，第二完成人（2/10）； 2010年，提高出生人口质量的生殖技术创建、体系优化与临床推广应用，中华人民共和国国务院，国家科学技术进步奖二等奖，第一完成人（1/10）。 2022年，生殖障碍精准诊疗、促进子代健康关键技术体系的创建与推广应用，浙江省人民政府，浙江省科学技术进步奖一等奖，第二完成人。 2019年，发育源性疾病和遗传性出生缺陷的机制研究及临床精准防控，上海市人民政府，上海市科技进步奖一等奖，第一完成人（1/15）； 2019年，针刺和中药组合物在体外受精-胚胎移植中的规范化应用，浙江省人民政府，浙江省科学技术进步奖二等奖，第二完成人（2/9）； 2010年，阻断出生缺陷、促进子代健康关键技术体系的创建与推广应用，浙江省人民政府，浙江省科学技术奖一等奖，第一完成人（1/13）； 2007年，子宫内膜异位症与女性不孕症的研究，浙江省人民政府，浙江省科学技术奖二等奖，第一完成人（1/9）； 2007年，妊娠高血压疾病的临床与基础研究，浙江省人民政府，浙江省科学技术奖三等奖，第四完成人（4/7）； 2004年，辅助生育技术基础和临床系列研究，浙江省人民政府，浙江省科学技术奖一等奖，第一完成人（1/13）； 2003年，造血干/祖细胞体外扩增新技术体系，浙江省人民政府，浙江省科学技术奖三等奖，第四完成人（4/7）； 2001年，胚胎冻存复苏移植，浙江省人民政府，浙江省科学技术进步奖二等奖，第二完成人（2/7）； 2000年，米非司酮配伍米索前列醇药物流产后异常子宫出血机理研究，浙江省人民政府，浙江省科学技术进步奖三等奖，第四完成人（4/5）； 1996年，辅助生育技术（试管婴儿），浙江省人民政府，浙江省科学技术进步奖二等奖，第三完成人（3/4）。 2018年，安全高效辅助生殖技术体系的构建与推广应用，教育部，高等学校科学研究优秀成果奖科技进步奖二等奖，第二完成人，2018-257 2015年，生殖过程调控及相关疾病分子机理，全国妇幼健康科学技术奖一等奖，第一完成人； 2011年，提高出生人口质量的生殖技术创建、体系优化与临床推广应用，全国人口/计划生育“十一五”优秀科技成果一等奖，第一完成人。
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